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6¸öÔµÄGLP-1ÊÜÌ弤¶¯¼Á£¨GLP-1RA£©ÖÎÁÆ¿ÉÒÔ¸ÄÉÆÇá¶ÈÖÁÖÐ¶È DKD »¼ÕßµÄѪÌÇ¡¢ÑªÑ¹¡¢ÑªÖ¬ºÍÌåÖØ £¬£¬£¬ £¬£¬Í¬Ê±¼õ»ºÉöÔ༲²¡µÄÉú³¤¡£¡£ ¡£¡£¡£¡£Ëü×ÔÁ¦ÓÚѪ¹ÜÖ÷ÒªËØ×ª»»Ã¸ÒÖÖÆ¼Á£¨ACEi£©/Ѫ¹ÜÖ÷ÒªËØÊÜÌåÞ׿¹¼Á£¨ARB£©µÄÓ°Ïì¶ø½µµÍÂѰ×Äò £¬£¬£¬ £¬£¬²¢ÇÒÔçÆÚʹÓÿÉÒÔ¸ü¿ì±¬·¢Ð§¹û £¬£¬£¬ £¬£¬ÕâÖ§³ÖÁË»ùÓÚÖ¤¾ÝµÄÁÙ´²Êµ¼ù¡£¡£ ¡£¡£¡£¡£


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[1] Ying Liu et al. Real-world clinical effectiveness of glucagon-like peptide-1 receptor agonist on mild-to-moderate diabetic kidney disease in patients with type 2 diabetes: a retrospective, single-arm clinical trial.Diabetes, Metabolic Syndrome and Obesity 2024:17 2913¨C2921. 

[2] Mohandes S, Doke T, Hu H, et al. Molecular pathways that drive diabetic kidney disease. J Clin Invest. 2023;15;133:e165654. 

[3] Bonner R, Albajrami O, Hudspeth J, et al. Diabetic kidney disease. Prim Care. 2020;47:645-659.

[4] Mima A, Nomura A, Fujii T. Current findings on the efficacy of incretin-based drugs for diabetic kidney disease: a narrative review. Biomed Pharmacother. 2023;165:115032.

[5] Cao Y, Cao S, Zhao J, Zhao J, Zhao Y and Liu Y (2024) Efficacy and safety of polyethylene glycol loxenatide in treating mild-to-moderate diabetic kidney disease in type 2 diabetes patients: a randomized, open-label, clinical trial.Front. Endocrinol. 15:1387993.


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